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Oprah Winfrey announces plans to end The Oprah Winfrey Show after the 2010–2011 season, 2009. Photo Credit: Harpo, Inc./George Burns.

Oprah Winfrey waves to the audience on the final episode, 2011. Photo Credit: Harpo, Inc./George Burns.

Civil Rights Legends Honorees, 2014 Standing, left to right: Rep. John Lewis, Julian Bond, Sidney Poitier, Oprah Winfrey, Quincy Jones, Dick Gregory, and Berry Gordy. Seated, left to right: Ambassador Andrew Young, Diane Nash, Juanita Jones Abernathy, Rev. Joseph Lowery, Myrlie Evers-Williams, Marian Wright Edelman, and Rev. C. T. Vivian. Photo Credit: Harpo, Inc./George Burns

Freedom Riders Reunion, 2011: Rep. John Lewis (center) appeared on this episode with Elwin Wilson, a white supremacist who apologized in 2009 for assaulting Lewis and another Freedom Rider in 1961. Photo Credit: Harpo, Inc./George Burns

Morehouse Oprah Scholars on stage with Oprah Winfrey at “Surprise Oprah! A Farewell Spectacular,” 2011. Photo Credit: Harpo, Inc./George Burns.

Harpo Studios production staff and crew greet Oprah Winfrey backstage after the taping of the final episode of The Oprah Winfrey Show, 2011. Photo Credit: Harpo, Inc./George Burns.

Stylists Derrick Rutledge and Andre Walker work on Oprah Winfrey’s hair and makeup before a show, 2011. Photo Credit: Harpo, Inc./Joe Pugliese.

Oprah Winfrey in her office at Harpo Studios, Chicago, 2011. Photo Credit: Harpo, Inc./Joe Pugliese

“Oprah and Gayle’s Big Yosemite Camping Adventure” set, 2010. Photo Credit: Harpo, Inc./George Burns.

Edible set made out of Godiva chocolate, 2010. Photo Credit: Harpo, Inc./George Burns.

Re-creation of The Mary Tyler Moore Show set, 2008. Photo Credit: Harpo, Inc./George Burns.

Oprah Winfrey interviews Houda, a woman from Mauritania, on the “Beauty Secrets from Around the World” episode of The Oprah Winfrey Show, 2008. Photo Credit: Harpo, Inc./George Burns.

Announcing the launch of Oprah & Friends on XM Satellite Radio, 2006. Photo Credit: Harpo, Inc.

Sen. Barack Obama discusses his book, The Audacity of Hope, on The Oprah Winfrey Show, 2006. Photo Credit: Harpo, Inc./George Burns.

Jamie Foxx presents portrait of Oprah Winfrey by Artis Lane, 2005. Photo Credit: Harpo, Inc./George Burns.

Oprah Winfrey with young O Ambassadors, an international student program sponsored by Oprah’s Angel Network and Free the Children, 2008. Photo Credit: Harpo, Inc./George Burns.

Oprah’s Angel Network helps to build new homes for families left homeless by Hurricane Katrina, Houston, Texas, 2005. Photo Credit: Harpo, Inc./George Burns.

Nate Berkus does an interior design makeover on The Oprah Winfrey Show, 2007. Photo Credit: Harpo, Inc./George Burns.

Oprah Winfrey’s 50th birthday episode, 2004. Photo Credit: Harpo, Inc./George Burns.

Rachael Ray demonstrates a recipe on The Oprah Winfrey Show, 2006. Photo Credit: Harpo, Inc./George Burns.

“Oprah’s Ultimate Favorite Things” episode, 2010. Photo Credit: Harpo, Inc./George Burns.

Ready for the “Ultimate Australian Adventure,” The Oprah Winfrey Show, 2010. Photo Credit: Harpo, Inc./George Burns.

Oprah Winfrey and audience members with new cars, 2004. Photo Credit: Harpo, Inc./George Burns.

Oprah Winfrey pulls a wagon representing the 67 pounds of fat she lost on a liquid diet, 1988. Photo Credit: Harpo, Inc.

Patti LaBelle and Oprah Winfrey, 1996. Photo Credit: Harpo, Inc./George Burns.

Inspirational speaker Iyanla Vanzant with Winfrey during a “Remembering Your Spirit” segment on The Oprah Winfrey Show, 1999. Photo Credit: Harpo, Inc./George Burns.

Announcing the first Oprah’s Book Club selection, 1996. Photo Credit: Harpo, Inc./George Burns.

Oprah Winfrey and her crew traveled to Naperville, Illinois, to announce the new Book Club selection—John Steinbeck’s East of Eden—at a local independent bookstore. Photo Credit: Harpo, Inc./George Burns.